SYNAPTOTAGMIN 7 SWITCHES SHORT-TERM SYNAPTIC PLASTICITY FROM DEPRESSION TO FACILITATION BY SUPPRESSING SYNAPTIC TRANSMISSION

Synaptotagmin 7 switches short-term synaptic plasticity from depression to facilitation by suppressing synaptic transmission

Abstract Short-term synaptic plasticity is a fast and robust modification in neuronal presynaptic output that can enhance release strength to drive facilitation or diminish it to promote depression.The mechanisms that determine whether neurons display short-term facilitation or depression are still unclear.Here we show that the Ca2+-binding protein

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UvATG6 Interacts with BAX Inhibitor 1 Proteins and Plays Critical Roles in Growth, Conidiation, and Virulence in Ustilaginoidea virens

ABSTRACT Autophagy and apoptosis are evolutionarily conserved catabolic processes involved in regulating development and cellular homeostasis.Bax inhibitor 1 (BI-1) and autophagy protein 6 (ATG6) perform essential functions in these roles, such as cellular differentiation and virulence in various filamentous fungi.However, the functions of ATG6 and

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